Several biomarkers have been identified for HCC, such as alpha-fetoprotein (AFP), apyrimidinic endodeoxyribonuclease 1 (APEX1), glypican 3 (GPC3), Dickkopf-1 (DKK1), and Golgi protein-73 (GP73) (10–14). This evidence concerns the gene GPC3 and hepatocellular carcinoma.