GAD1 and type 1 diabetes mellitus: If the patient has a fasting glucose > 200, random > 250 or a history of T2DM with a fasting/random >250, patients should be considered to have new onset T1DM, which requires comprehensive T1DM laboratory panel (C-peptide and anti-GAD, anti-islet cell antibodies) and an evaluation for DKA (blood pH, BMP, urine/serum ketones, anion-gap, BHB) (26, 32).