Furthermore, it has been reported that activated B cells express several other TNFSF ligands, including TNF, Fas ligand (FasL), TRAIL, OX40L, CD30L, CD40L CD70, LIGHT, GITRL, BAFF and APRIL (14–17) and, therefore, they might be capable of mediating various innate immune functions, including killing of cancer cells. The gene discussed is FASLG; the disease is cancer.