DTL and hepatocellular carcinoma: Our explorations into the role of DTL in HCC were based on preexisting data from the GEO, TCGA, and TIMER databases, and some of our findings were verified by our validation cohort; however, we did not conduct in vivo and in vitro experiments to confirm the function of DTL in the biological processes of the cell cycle and DNA replication or its relationship with the infiltrating immune cells in TME, which pinpoint the direction for our future work.