Obviously, the expression of G6PD was significantly higher in colon adenocarcinoma (COAD), LIHC, pancreatic adenocarcinoma (PAAD), rectum adenocarcinoma (READ), skin cutaneous melanoma (SKCM), and stomach adenocarcinoma (STAD) but was lower in acute myeloid leukemia (LAML), and testicular germ cell tumors (TGCT). Here, G6PD is linked to cutaneous melanoma.