IGFL2 and endometriosis: NTM, one of the target gene of lncRNA IGFL2-AS1, was shown in our GSEA analysis to participate in the epithelial-mesenchymal transition of EMS (Supplementary Material) Increasing numbers of experiments have improved that EMT is involved in inducing the invasion and migration of endometrial epithelial cells, and this process is of great significance in establishment of endometriosis (Matsuzaki and Darcha, 2012).