By contrast, SMARCB1 only reported three LoF variants in the non‐cancer gnomAD cohort (Ensembl canonical transcript ENST00000263121.7, Accessed February 3, 2022), which means that there were 3 from a mean of 118,374 individuals (1 in 39,458) with an LoF variant. The gene discussed is SMARCB1; the disease is cancer.