Gamma induction may be neuroprotective against neurodegenerative diseases (Adaikkan et al., 2019; Martorell et al., 2019) and animal models of Alzheimer's disease have allowed to demonstrate that repetitive sensory gamma entrainment improves the function of fast-spiking parvalbumin-positive interneurons as well as microglia. The gene discussed is PVALB; the disease is early-onset autosomal dominant Alzheimer disease.