Second, we showed previously that methylation of the promoter regulates PEAR1 expression [13], but in view of Belgian privacy regulations, currently tightened by the European General Data Protection Regulation (https://ec.europa.eu/info/law/law-topic/data-protection/eu-data-protection-rules_en), we were not granted access to the biopsies from the cancer cases included in our current study. The gene discussed is PEAR1; the disease is cancer.