Furthermore, the present study found that glucose stimulates MCP-1 mRNA levels in human adipocytes, this is in agreement with the literature showing that high glucose increased MCP-1 production in human vascular endothelial cells [36], indicating that hyperglycemia may play a major role in enhancing MCP-1 expression in OMAT and directly triggers the recruitment of macrophages to adipose tissues. The gene discussed is CCL2; the disease is Hyperglycemia.