CASC3 and Miyoshi myopathy: Through flow cytometry assay, we observed the combination treatment of MLN8237 and BTZ induced more apoptosis of LP‐1 and KMS‐11 cells compared with MM.1S and 8226 cells (Figure 1E,F), and the differences were even more significant in the t(4;14) positive MM cells, either with lower dose (1nM) or higher dose (5nM) of BTZ (Figure 1G,H).