FGFR2 and lung carcinoma: FGFR1 belongs to thetyrosine kinase receptor family, which is responsible for regulatingmany crucial processes of organism development and cellular metabolism.52,53 Overexpression of FGFR1 has been reported, among others, in breastand lung cancer, making it a promising target for therapy.54 Two FGFR-targeting ADCs have been studied inphase I clinical trials, LY3076226 (NCT02529553) and BAY1187982 (NCT02368951),specific for FGFR3 and FGFR2, respectively.