Within this set of genes, we identified five genes targeted by one of 12 clinical available NIRF tracers: MET (ranked 11; tumor-specific target of the clinically available NIRF tracer EMI-137), PSMA 7 and PSMA 1 (ranked 685 and 1070; targets of MDX1201-A488), and CTSK and CTSH (ranked 668 and 1672; targets of LUM015). The gene discussed is CTSK; the disease is neoplasm.