Age (P = 0.889), sex (P = 0.233), smoking history (P = 0.543), tumor location (P = 0.141), hemoglobin (P = 0.486), fibrinogen (P = 0.699), preoperative CA199 level (P = 0.486), the ratio of neutrophils to lymphocytes (P = 0.350), and the ratio of fibrinogen to prealbumin (P = 0.325) were not associated with lymph node metastasis in stage T1 colorectal cancer (Table 1). Here, TTR is linked to colorectal cancer.