PPARG and obesity due to melanocortin 4 receptor deficiency: Some of the EDCs are tributyltin, diethylstilbesterol, dichlorodiphenyltrichloroethane (DDT), phytoestrogens, parabens, etc. The transcription factors such as peroxisome proliferator-activated receptors (PPARs) are classified into PPAR gamma, alpha, and epsilon, which regulate and control genome throughout the life wherein EDCs binding with nuclear receptors of PPAR gamma is related to obesity.