For PFS, the univariate analysis showed that the variables ALT (HR 1.004, 95% CI 1.000–1.014; P = 0.027), leukocytes (HR 1.125; 95% CI 1.039–1.219; P = 0.004), tumor size (HR 1.055, 95% CI 1.016–1.095; P = 0.005), TACE session (HR 0.198, 95% CI 0.122–0.322; P < 0.001), portal invasion (HR 2.759, 95% CI 1.889–4.029; P < 0.001), Child–Pugh (HR 2.181; 95% CI 1.457–3.263; P < 0.001), ECOG (1 vs 0: HR 3.322, 95% CI 2.076–5.316; P < 0.001; 2 vs 0: HR 7.222, 95% CI 4.255–12.257; P < 0.001), and HR 0.559, 95% CI 0.389–0.804; P = 0.002) might influence tumor progression. This evidence concerns the gene GPT and neoplasm.