ABL1 and acute lymphoblastic leukemia: Based on this analysis, an AKR1C3 RNA expression threshold of 2.62 (normalized ratio to ABL1) to differentiate diagnostic T-ALL specimens and this MRD/post-treatment would give us a t-test P value of 0.0001, with a 95% confidence interval from − 3.733065 to − 1.854085.