Finally, our use of the composite CKD outcome makes it difficult to examine the relationships between each nutrient and incident decreased eGFR (< 60 ml/min/1.73 m2 with > 1 ml/min/1.73 m2 decline) or incident albuminuria (albumin to creatinine ratio ≥ 30 mg/g) independently. The gene discussed is ALB; the disease is chronic kidney disease.