The 14-3-3 protein family regulates critical growth-regulatory pathways.25 This family has distinct subtypes; 14-3-3ζ protein has oncogenic effects in breast, lung cancer, liver, and pancreatic cancers.25,43–46 Post-translational modifications affect 14-3-3ζ protein. The gene discussed is YWHAQ; the disease is familial pancreatic carcinoma.