SARS-CoV-2, the causal agent of COVID-19, enters human cells using the ACE2 (angiotensin-converting enzyme 2) protein as a receptor.1–5 ACE2 is highly expressed in the heart, respiratory, and gastrointestinal tracts, and it plays important regulatory roles in the cardiovascular and other biological systems.6 ACE2 proteolytically degrades angiotensin II (a potent vasoconstrictive, proinflammatory, and prothrombotic mediator) into angiotensin-(1–7), thereby regulating blood pressure, salt and water balance, glucose homeostasis, and amino acid absorption in the kidney and small intestine. Here, ACE2 is linked to COVID-19.