CYP19A1 and disease of the tendon: Although previous studies showed no relationship between statin use and tendon rupture (Spoendlin et al., 2016; Contractor et al., 2015; Beri et al., 2009), clinicians must be aware of the possible risk of tendon disorders when administering fluoroquinolones to patients taking statins, aromatase inhibitors, or glucocorticoids.