We also observe, in contrast to what was observed in the rhodopsin-mediated RP mouse models, a substantial increase in the levels of SOCS3 in the BXD32 mouse retina compared to WT retinas, indicating, in conjunction with phosphorylation at Ser727, a possible attempt to lessen or control the proinflammatory signaling. Here, RHO is linked to retinitis pigmentosa 1.