After calculating the hazard ratio and confidence interval, we observed that 8 hub genes in hub network 1 were related to the poor prognosis of gliomas, including PBK, KIF2C, CENPE, KIF14, MND1, FAM83D, NEIL3, and CDKN3 (Figure 4(a)). Here, CDKN3 is linked to central nervous system cancer.