NOS3 and type 2 diabetes mellitus: Therefore, Zheng et al. (51) performed an RCT to study the gene-diet interaction of CD36 (rs1527483), NOS3 (rs1799983), and PPARγ (rs1801282) in response to supplements of omega-3 fatty acids (from fish oil: 2 g/day of C20:5ω-3 and C22:6ω-3, or flaxseed oil: 2.5 g/day of C18:3ω-3) in blood lipids of adults with T2D.