Compared to ctrl and AD groups, Hp, C1, and RBP4 were upregulated in patients with DOCK8 deficiency (Figures 4A–C), whereas Apo A1 was upregulated in AD compared to patients with DOCK8 deficiency, and ctrls (Figure 4D). Here, RBP4 is linked to hyperinsulinemic hypoglycemia, familial, 4.