DOCK8 and Alzheimer disease: For the purpose of evaluating potential biomarkers highlighted in the proteomics profile, the significantly differentially regulated proteins (FDR p-value < 0.05, FC cut-off 2) among DOCK8 vs. ctrls (n = 109), AD vs. Ctrls (n = 105), and DOCK8 vs. AD (n = 85) were overlapped.