Stratified Kaplan–Meier survival analysis and log rank tests were performed using the radiomics signature to further identify different risk subgroups among different clinical subgroups (younger or older, male or female, GBM or non-GBM) and molecular subgroups (IDH mutation or wild-type, MGMT promoter methylation or nonmethylation). This evidence concerns the gene MGMT and glioblastoma.