Among three SII tertiles, differences with statistical significance were observed in age, gender, race, smoking status, physical activity, BMI, SBP, DBP, diabetes, hypertension, SCr, total cholesterol, HDL-C, ALT, AST, waist circumference, triglycerides, eGFR, urinary albumin, and ACR (all p<0.05). The gene discussed is ALB; the disease is hypertensive disorder.