However, interferon induced genes like RSAD2 and IFIT2 (interferon induced protein with tetratricopeptide repeats 2) that were also strongly upregulated in response to BG treatment can also be induced by several other signalling pathways including Toll-like receptor 3, virus infection or pathogen-associated molecular patterns (PAMPs) [52]. The gene discussed is RSAD2; the disease is viral infectious disease.