ATXN3 and Huntington disease: Such TDP-43 proteinopathy has not traditionally been associated with polyQ diseases, but inclusions have in fact been reported in SCA3 (Tan et al., 2009; Seidel et al., 2010), SCA2 (Toyoshima et al., 2011; Mori et al., 2014) and Huntington’s disease patients (Schwab et al., 2008; St-Amour et al., 2018; Sanchez et al., 2021).