In short, the non-invasive scores (AST/ALT ratio, APRI score, FIB-4 index and NAFLD-fibrosis score), especially FIB-4 index and NAFLD-fibrosis score can be used reliably in routine practice to exclude or rule out liver fibrosis in individuals with DM and metabolic syndrome. Here, GPT is linked to metabolic dysfunction-associated steatotic liver disease.