The patient was diagnosed with a rare small cell neuroendocrine carcinoma, which makes up less than 3% of all cervical cancers. It can affect women aged 22 to 87 years old, the mean age being 45 years old, with some cases linked to HPV 16 and 18 [5-7]. It often presents as vaginal bleeding, pelvic pressure, or low back pain, with metastasis to regional lymph nodes in the early stages [5,6,8]. Definitive diagnosis is made via biopsy staining for at least two neuroendocrine tumor markers such as synaptophysin, CD56, chromogranin, and NSE [5]. Here, ENO2 is linked to cervical cancer.