BACE1 and cancer: For instance, Wang M. et al. (2021) using expression patterns and survival data in 32 cancer types retrieved from the cBioPortal1 and Cancer Genome Atlas2 found that BACE1-AS is significantly upregulated in various human malignancies, such as glioblastoma, liver hepatocellular carcinoma (HCC), kidney renal clear cell carcinoma, and colon adenocarcinoma.