TGM2 and Abnormal intestine morphology: To conclusively address whether anti-TG2 antibodies as found in the serum of celiac patients play a direct role in the development of enteropathy, we injected TG2-sufficient and TG2-deficient mice with murine IgG or IgA harboring the variable domains of the prototypic celiac anti-TG2 antibody 679-14-E06 (from here denoted 14E06) [17].