Although our sample size was small, we found results very similar to those from other studies.(12) Gust et al., also reported FGFR3 mutations in 11% of patients, in a similar cohort from Europe, with Greek and Spanish patients.(13) Another study found 6% of mutations.(14)These numbers are much fewer than those found in non-invasive and low-grade bladder cancer.(4). The gene discussed is FGFR3; the disease is urinary bladder cancer.