BALB/c mice infected for 35 days had similar parasite burdens in spleen and liver as assessed by read counts for Amastin (LdBPK_080710.1 in the L. donovani BPK reference and L. infantum orthologue LINF_080012100; Fig. 1B) and similar degrees of hepatosplenomegaly, as assessed by organ weight (Fig. 1C). The gene discussed is BTK; the disease is Hepatosplenomegaly.