Common variants in our WAA cohorts were identified in cancer-associated genes—NBPF12, PLIN4, TP53, ZNF717, TAP1, KMT2D, PIEZO1 and BRCA1 (Fig. 2C, Table S5) as well as in HMCN2 and MBD3L3 which have not been previously associated with cancer. The gene discussed is HMCN2; the disease is cancer.