In summary, the changes in 10‐h LH pulse frequency, mean LH, LH AUC, pulsatile LH secretion, basal LH secretion, LH half‐life, mean FSH, and FSH AUC attributable to progesterone were similar between the control and PCOS groups after adjusting for differences in achieved progesterone and estradiol concentrations. This evidence concerns the gene PLOD1 and polycystic ovary syndrome.