The role of Wnt/β‐catenin signalling inactivation in the pathogenesis of T2DM was further indicated by the elevation of Dickkopf‐1 (DKK‐1), a Wnt/β‐catenin signalling antagonist, in the serum of a patient with T2DM.10, 11. This evidence concerns the gene DKK1 and type 2 diabetes mellitus.