It was noted that in the new-onset patients with pulmonary tuberculosis, thick-walled bacilli were negatively correlated with CD4+/CD8+ and CD14+CD16+ and are positively correlated with CD14+CD16-; at the genus level, Enterococcus faecalis was positively correlated with CD4+/CD8+ and CD4+43. This evidence concerns the gene CD14 and pulmonary tuberculosis.