Western blot data showed that the values of p-JNK/JNK and JNK/GAPDH were significantly higher in rhoifolin-treated PANC-1 and ASPC-1 cells than that in the control group, indicating that rhoifolin could induce the JNK pathway in the apoptosis of pancreatic cancer cells. Here, MAPK8 is linked to pancreatic neoplasm.