GBP2 and colorectal carcinoma: Considering the very disappointing data in stage IV CRC with ICB, we analyzed the relationship between GBP2 and metastasis in the GSE131418 dataset, which contains 878 primary CRCs and 257 metastatic CRCs.24 The results revealed that the number of metastatic patients were significantly higher in the GBP2 low expression group (35.1%, 199/567) compared with the high expression group (10.2%, 58/568) (figure 2J).