Circ_0001955 promotes HCC cell progression through sponging miR-516a-5p to enhance the expressions of TRAF6 and MAPK11 [36]; circ_102559 sequesters miR-130a-5p to propel HCC cell progression by up-regulating ANXA2 expression [37]; and circ_0091570 serves as a ceRNA to inhibit the progression of HCC via sequestering miR-1307 [38]. Here, ANXA2 is linked to hepatocellular carcinoma.