Stem cell potency-associated members were applied for expression identification using the CBIOPORTAL, and the profiled patterns of different studies are shown in Figure 2, which has emphasized a good concordance of the four members of PGP9.5, SOX2, TP53 and CAGE with the surface markers of cancer stem cells of either PROM1, CD44 or ALDH1A1. The gene discussed is ALDH1A1; the disease is cancer.