However mortality in this model is more closely linked to the magnitude and quality of the inflammatory response and indeed we found mice lacking MAIT cells had a deficiency SigF+CD11bintCD64+CD11c+alveolar macrophages at 3 days post infection associated with reduced total pulmonary T cells numbers by day 5, and evidence of impaired antigen-specific CD8+ T cell responses at days 7 and 9. This evidence concerns the gene CD8A and infection.