CDH13 and breast carcinoma: Wang et al. (130) examined methylation levels in CpG islands of candidate genes among Black and White breast cancer patients and found racial differences in methylation for the CDH13 gene, which were more pronounced among Black patients with early onset of estrogen receptor (ER)-negative breastcancer comparedtomatched Whitepatients.Moreover,methylation levelsat three genes (CDH13,RASSF1A,and RARb2) were higher among Black women than among White women and were associated with lower survival (130).