This study identified several new susceptibility loci reached genome-wide significance, IL1A-IL1B, ADO-EGR2, CEBPB-PTPN1, IRF8, LACC1, and RIPK2. A few loci previously reported for BD were also replicated, including HLA-B*51, CCR1, ERAP1, FUT2, IL10, IL12A, IL23R-IL12RB2, and KLRC4 [37]. The gene discussed is IL23R; the disease is Behcet disease.