IFNG and neoplasm: Elevated infiltration of activated immune cells, in turn, resulted in higher levels of Th1-related cytokines and chemokines (Fig. 3l), and higher infiltration of IFN-γ (Fig. 3m) and IL-2 expressing (Fig. 3n) T cells in the tumour tissues after CAR(NAP) T-cell treatment compared with CAR T-cell treatment.