To establish suitable models to investigate KBTBD4, we assessed endogenous CoREST and LSD1 protein levels in five representative medulloblastoma cell lines of different subgroups: D283Med (group 3/4, without reported MYC amplification), HD-MB03 (group 3, MYC amplification), D425Med (group 3, MYC amplification), D458Med (metastatic counterpart of D425Med primary tumour) as well as DAOY (SHH subgroup). The gene discussed is MYC; the disease is medulloblastoma.