In COVID-19-ARDS patients, the total number of DEspR+CD11b+ NET-forming neutrophils correlated strongly with three clinical measures: 1] outcome at day-28 (ICU-free days at day 28), 2] degree of hypoxemia (SpO2/FiO2 or S/F ratio), and 3] severity of multi-organ failure score at end of ICU-stay (t2-SOFA), but not with t1-SOFA (Table 2, Fig. 5I). This evidence concerns the gene ITGAM and acute respiratory distress syndrome.