First, we ascertained DEspR-specific immunotyping of whole blood samples from ARDS patients by validating our gating strategy for flow cytometry (Supplementary Fig. S4A–E), DEspR-specific detection in duplicates (Supplementary Fig. S4F–I) and reproducibility in triplicates (Fig. 4A, Supplementary Fig. S4J). Here, FBXW7-AS1 is linked to acute respiratory distress syndrome.