MCL1 and cancer: Based on insights from the study of DEspR+ cancer stem-like cells (CSCs) exhibiting aberrant apoptosis-resistance associated with myeloid cell leukemia (Mcl1) levels, a key apoptosis-evasion protein in cancer18, we reasoned that DEspR+ neutrophils would also have survival advantages as Mcl1 levels correlate with neutrophil survival19.