MYCN and neuroblastoma: By comparing the level of EIF4EBP1 in MYCN-amplified versus MYCN-non-amplified NB samples, we found that EIF4EBP1 is expressed at higher levels in MYCN-amplified compared to MYCN-non-amplified NB in the SEQC and Kocak cohorts [43, 44] (p < 0.0001, Fig. 1b; p < 0.0001, Fig. 1c).